Aldactone 25 is a potassium-sparing diuretic drug that increases the excretion of chlorine, sodium and water, while reducing the output of potassium and urea, as well as titrated uric acid. Spironolactone tablets show their diuretic effect at 2-5 days of therapy.
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Indications for use Aldactone 25:
- Premenstrual syndrome;
- Polycystic ovary syndrome;
- Aldosterone-producing adrenal adenoma;
- Primary hyper aldosteronism;
- Arterial hypertension;
- Swelling in the second and third trimester of pregnancy;
- Nephrotic syndrome;
- Cirrhosis of the liver;
- Swelling on the background of chronic heart failure.
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In the case of essential hypertension for adults, a single daily dose of Aldactone 25 is about 50-100 mg but you can increase it to 200 mg. Increasing the dose should be 1 to every 14 days. For an adequate result of therapy, it is necessary to take the drug for at least 2 weeks. If necessary, you may need to adjust the dose.
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The use of Aldactone 25 is contraindicated in Addison’s disease, hyperkalemia, hypercalcemia, hyponatremia, chronic renal failure, anuria, liver failure, diabetes mellitus, diabetic nephropathy, metabolic acidosis, disorders of the menstrual cycle, breast enlargement and hypersensitivity to Spironolactone.
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It is known that Aldactone 25 and its metabolites penetrate the human placental barrier and are excreted in breast milk; therefore, during pregnancy and breastfeeding the drug should not be used.