Premarin is a drug that eliminates the manifestations of the climacteric syndrome, prevents the development of osteoporosis, prevents the involution of the genital organs, normalizes the menstrual cycle in women of childbearing age and reduces the level of testosterone in men.
Before you start taking Premarin, you should conduct a thorough medical and gynecological examination, including the examination of the mammary glands and the implementation of a vaginal Pap smear for the detection of malignant cells.
The average dose of Premarin for cyclic use is 0.625-1.25 mg per day. The cycle duration is 21 days with a break of 7 days for all indications, except for certain cases: carcinomas of the mammary gland, prostate gland and prevention of lactostasis. With continuous treatment, the drug is taken daily for 1 reception.
Possible side effects from Premarin include: headache, nausea, vomiting, weight gain, edema, uterine bleeding, skin pigmentation of the face, erythema nodosum, transient increase in plasma transaminase levels and hyperbilirubinemia.
Contraindications to the use of the drug are: breast cancer and estrogen-dependent tumors; uterine bleeding of unknown etiology; thrombophlebitis, a violation of the blood coagulation system, thromboembolic diseases; severe diseases of the cardiovascular system; severe impaired liver or kidney function; sickle cell anemia; congenital hearing loss; prolonged immobilization.